The Research
This list reflects research that the lab was built on that was done by Dr. Martin and the research coming out of the lab. It does not reflect the countless collaborative publications that Dr. Martin’s lab has worked on with other investigators.
Tharakan A, Kumar A, Camarena C, Conrad DH, & Martin RK. D-2-hydroxyglutarate attenuates sinonasal inflammation in murine allergic rhinitis. Allergies. May 2025.
Tharakan A, Rodriguez-Agudo D, Damle S, Kakiyama G, Pandak W, Gil G, & Martin RK. StarD5 modulates B cell cholesterol synthesis and IgG1 plasma cell differentiation. BBRC Reports. Nov 2024.
Tharakan A, Kumar A, Allegood J, Cowart LA, Conrad DH, & Martin RK. D-2-hydroxyglutarate suppresses allergic sensitization in a murine model of experimental asthma. Allergy. Nov 2023.
Way GW, Camarena C, Sarkar D, Martin RK*, & Zhou H*. Optimization of High Throughput Spectral Flow Cytometry for Immune Cell Profiling in Mouse Liver. Liver Research. Sept 2023.
James BN, Weigel C, Green CD, Brown RDR, Palladino END, Tharakan A, Milstein S, Proia RL, Martin RK*, & Spiegel S*. Neutrophilia in Severe Asthma is reduced in Ormdl3 Overexpressing Mice. FASEB Journal. Mar 2023.
Farrar JS, & Martin RK. Isolation of the Stromal Vascular Fraction from Adipose Tissue and Subsequent Differentiation into White or Beige Adipocytes. Methods Mol Biol. 2022.
Farrar JS, Lownik JC, Way GW, Rodriguez MC, Celi FS, & Martin RK. Identification of the transgene insertion site for an adipocyte-specific adiponectin-cre model and characterization of the functional consequences. Adipocyte. Dec 2021.
Lownik JC, Way GW, Farrar JS, & Martin RK. Extraction-Free Rapid Cycle Quantitative RT-PCR and Extreme RT-PCR for SARS-CoV-2 Virus Detection. J Mol Diagn. Dec 2021.
Lownik JC, Farrar JS, Way GW, McKay A, Roychoudhury P, Greninger AL, Martin RK. Fast SARS-CoV-2 Variant Detection Using Snapback Primer High-Resolution Melting. Diagnostics (Basel). Sep 2021.
Lownik JC, Farrar JS, Pearce JV, Celi FS, & Martin RK. Adipocyte ADAM17 plays a limited role in metabolic inflammation. Adipocyte. Dec 2020.
Lownik JC, Conrad DH, & Martin RK. T cell receptor signaling defines the fate and pathway of ICOS internalization. Biochem Biophys Rep. Dec 2020.
Smith TM Jr, Tharakan A, & Martin RK. Targeting ADAM10 in Cancer and Autoimmunity. Front Immunol. 2020.
Luker AJ, Graham LJ, Smith TM Jr, Camarena C, Zellner MP, Gilmer JS, Damle SR, Conrad DH, Bear HD, & Martin RK. The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive immunotherapy in a mouse model of breast cancer. BMC Immunol. Feb 2020.
Lownik JC, Wimberly JL, Takahashi-Ruiz L, & Martin RK. B cell ADAM17 controls T cell independent humoral immune responses through regulation of TACI and CD138. Biochem Biophys Res Commun. Feb 2020.
Luker AJ, Lownik JC, Conrad DH, Martin RK. A new look at IgE beyond allergies. F1000Res. 2019.
Lownik JC, Conrad DH, & Martin RK. A Disintegrin and Metalloproteinase 17 is Required for ILC2 Responses to IL-33. Biochem Biophys Res Commun. Mar 2019.
Lownik JC, Wimberly J, Conrad DH, & Martin RK. B cell ADAM10 controls murine lupus progression through regulation of the ICOS:ICOS-ligand axis. 2019. J Immunol. Jan 2019.
Martin RK, Damle SD, Yolander VA, Zellner MP, James BN, Lownik JC, Luker AE, Davis EH, DeMeules MM, Khandjian LM, Finkelman FD, Urban JF & Conrad DH. B1 cell IgE impedes mast cell-mediated enhancement of parasite expulsion through B2 IgE blockade. Cell Rep. Feb 2018.
Lownik, JC, Luker, AJ, Damle, SR, Cooley, LF, El Sayed, R, Hutloff, A, Pitzalis, C, Martin, RK*, El Shikh, ME*, & Conrad, DH*. ADAM10-Mediated ICOS Ligand Shedding on B Cells Is Necessary for Proper T Cell ICOS Regulation and T Follicular Helper Responses. J Immunol. Aug 2017.
Damle, SR, Martin, RK, Cockburn, CL, Lownik, JC, Carylon, JC, Smith, AD, & Conrad, DH. ADAM10 and Notch1 on murine dendritic cells control the development of type 2 immunity and IgE production. Allergy. Aug 2017.
Damle, SR*, Martin, RK*, Cross, JV & Conrad, DH. Macrophage migration inhibitory factor deficiency enhances immune response to Nippostrongylus brasiliensis. Mucosal Immunol. Apr 2016.
Martin RK, Brooks KB, Henningsson F, Heyman B, & Conrad DH. Antigen transfer from exosomes to dendritic cells as an explanation for the immune enhancement seen by IgE immune complexes. Plos ONE. Oct 2014.
Martin RK*, Saleem SJ*, Folgosa LE, Zellner HB, Damle SR, Nguyen GT, Ryan, JJ, Bear, HD, Irani, AM, & Conrad, DH. Mast cell-histamine promotes the immunoregulatory activity of myeloid derived suppressor cells. J. Leukoc Biol. Mar 2014.
Saleem SJ*, Martin RK*, Morales JK, Sturgill JL, Gibb DR, Graham L, Bear, HD, Manjili, MH, Ryan, JJ, & Conrad, DH. Cutting edge: mast cells critically augment myeloid-derived suppressor cell activity. J. Immunol. July 2012
Chaimowitz NS*, Martin RK*, Cichy J, Gibb DR, Patil P, Kang, DJ, Farnsworth, J, Butcher, EC, McCright, B, & Conrad, DH. A disintegrin and metalloproteinase 10 regulates antibody production and maintenance of lymphoid architecture. J. Immunol. Nov 201.
* Denotes Co-Corresponding 2017-present, or Co-First Author 2011-2016